Pefloxacinum [Inn-Latin]
Brand names,
Pefloxacinum [Inn-Latin]
Analogs
Pefloxacinum [Inn-Latin]
Brand Names Mixture
Pefloxacinum [Inn-Latin]
Chemical_Formula
C17H20FN3O3
Pefloxacinum [Inn-Latin]
RX_link
No information avaliable
Pefloxacinum [Inn-Latin]
fda sheet
Pefloxacinum [Inn-Latin]
msds (material safety sheet)
Pefloxacinum [Inn-Latin]
Synthesis Reference
No information avaliable
Pefloxacinum [Inn-Latin]
Molecular Weight
333.358 g/mol
Pefloxacinum [Inn-Latin]
Melting Point
271 oC
Pefloxacinum [Inn-Latin]
H2O Solubility
11.4 mg/mL at 25 oC
Pefloxacinum [Inn-Latin]
State
Solid
Pefloxacinum [Inn-Latin]
LogP
1.49
Pefloxacinum [Inn-Latin]
Dosage Forms
No information avaliable
Pefloxacinum [Inn-Latin]
Indication
For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
Pefloxacinum [Inn-Latin]
Pharmacology
Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Pefloxacinum [Inn-Latin]
Absorption
Well absorbed by the oral route.
Pefloxacinum [Inn-Latin]
side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Pefloxacinum [Inn-Latin]
Patient Information
No information avaliable
Pefloxacinum [Inn-Latin]
Organisms Affected
Enteric bacteria and other eubacteria